Quality Standards and Antioxidant Activity of Siddha Formulation Cuvacakutori Chooranam

  • Achintya Kumar Mandal Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
  • Ramachandran Shakila Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
  • Sujith Thatipelli Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
  • Mattummal Rubeena Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
  • Kopala Narayanan Sunilkumar Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
  • Arumugam Thilagam Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
  • Rethinam Ganesan Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA
Keywords: Respiratory diseases, Cuvacakutori chooranam, Standardization, HPTLC, Antioxidant

Abstract

Objectives: To evaluate quality standards and to screen antioxidant activity of Cuvacakutori Chooranam (CC) a poly herbomineral Siddha formulation. Methods: The drug was prepared with authenticated ingredients. Powder microscopic, phytochemical, physicochemical, HPTLC fingerprint profiling (n-hexane, successive chloroform, successive ethanol), total phenol and flavonoid estimation, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging and superoxide scavenging activities of CC were studied. Results: Microscopic studies revealed diagnostic features to identify the formulation using microscope. Preliminary phytochemical screening revealed the presence of different secondary metabolites, unique chromatographic fingerprint and antioxidant activities. Conclusion: The powder microscopic characters and the evolved physicochemical data arrived could serve as a reference tool for quality control. The presence of different categories of phytochemicals and antioxidant activity of the drug gives broad scope for further efficacy studies of this drug.

Key words: Respiratory diseases, Cuvacakutori chooranam, Standardization, HPTLC, Antioxidant.

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Ingredients and powder microscopy of CC
Published
2019-11-05
How to Cite
1.
Mandal A, Shakila R, Thatipelli S, Rubeena M, Sunilkumar K, Thilagam A, Ganesan R. Quality Standards and Antioxidant Activity of Siddha Formulation Cuvacakutori Chooranam. ijpi [Internet]. 5Nov.2019 [cited 15Nov.2019];9(3):128-34. Available from: http://jpionline.phcog.interactivedns.com/index.php/ijpi/article/view/411